Chelsea won the tournament last season and two more Premier League sides are among the favourites to claim European victory
The Europa League has been whittled down to 16 teams, with possible paths to the final at Stadion Energa Gdansk in Poland being mapped out.
Arsenal were a high-profile exit from the last 32 having been beaten in extra-time by Olympiacos, while reigning champions Chelsea are featuring in the Champions League rather than the second-tier competition.
Who are the favorite teams to win the Europa League?
Manchester United are 4/1 (5.0) favourites with bet365 to win the Europa League for the second time in three years.
The Red Devils previously won Europe’s second-tier cup competition in 2017 once they defeated Ajax 2-0. The foremost recent trophy awarded to England’s most famous clubs.
Ole Gunnar Solskjaer’s side eased out of Group L and were handed one of the draws perceived to be more comfortable in the last-16, with United facing Austrian side LASK Linz.
Inter are the next favorite to win the Europa League after finishing third in their Champions League group and dropping into the second-tier competition.
The Italian side placed behind Barcelona and Borussia Dortmund in Group F and face a tough last-16 tie against Getafe, who are chasing a top-four finish in La Liga.
Wolves also are 13/2 (7.50) to mark their return to European football in impressive style by lifting their first major trophy since 1980.
Diogo Jota Wolverhampton 2019-20
The Premier League side were runners-up within the first-ever UEFA Cup – because it was known – in 1972, losing 3-2 to Tottenham on aggregate, and haven’t taken part in continental competition since 1981.
Nuno Espirito Santo’s side came second in a tough group and eased past Espanyol in the last-32 before being drawn against Olympiacos – conquerors of Arsenal – in the next round.
Sevilla are 7/1 (8.0) to keep up their position because the most dominant club in Europa League history by winning it for a sixth time.